Mar 17, 2026 | Chronicles
SkinChronicles, No 11, March 2026, by Haruna Kimura Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe cutaneous adverse reaction characterized by extensive keratinocyte death and epidermal detachment, yet the lesion-level immune circuitry...
Feb 17, 2026 | Chronicles
SkinChronicles, No 10, February 2026, by Alessia Paganelli For decades, clinical observations and smaller cohort studies have suggested that lichen sclerosus (LS) carries an increased risk of squamous cell carcinoma (SCC), particularly of the vulva. However, the true...
Jan 12, 2026 | Chronicles
SkinChronicles, No 9, January 2026, by Lavanya Moparthi Mass spectrometry–based spatial proteomics is an emerging approach that provides deeper molecular insights into biological processes at single‑cell resolution in situ. Nordmann and colleagues have advanced...
Nov 17, 2025 | Chronicles
SkinChronicles, No 8, November 2025, by Florence Assan Keratinocytes were known to participate in skin inflammatory responses by releasing proinflammatory cytokines such as IL-6, IL-8, and TNFα. In contrast, the production of type I interferons (IFNs) has...
Jun 10, 2025 | Chronicles
ESDR SkinChronicles, No. 7, June 2025, by Yaarob Altalli, MSc “Architectural Rewiring of the 3D Genome During Epidermal Differentiation” The mammalian nucleus condenses ~2 meter of DNA into a ~10 micrometre sphere, balancing extreme compaction with local...
Apr 14, 2025 | Chronicles
SkinChronicles, No 6, April 2025, by Attila Gábor Szöllősi Langerhans cells are, in my opinion, one of the most fascinating cells in the human body. They are cells positioned at both physical and conceptual boundaries. In the literal sense because they populate the...
