Nov 17, 2025 | Chronicles
SkinChronicles, No 8, November 2025, by Florence Assan Keratinocytes were known to participate in skin inflammatory responses by releasing proinflammatory cytokines such as IL-6, IL-8, and TNFα. In contrast, the production of type I interferons (IFNs) has...
Jun 10, 2025 | Chronicles
ESDR SkinChronicles, No. 7, June 2025, by Yaarob Altalli, MSc “Architectural Rewiring of the 3D Genome During Epidermal Differentiation” The mammalian nucleus condenses ~2 meter of DNA into a ~10 micrometre sphere, balancing extreme compaction with local...
Apr 14, 2025 | Chronicles
SkinChronicles, No 6, April 2025, by Attila Gábor Szöllősi Langerhans cells are, in my opinion, one of the most fascinating cells in the human body. They are cells positioned at both physical and conceptual boundaries. In the literal sense because they populate the...
Feb 12, 2025 | Chronicles
ESDR SkinChronicles, No. 5, February 2025, by Emanuele Scala The cytokine network has a pivotal role in maintaining skin homeostasis, and its dysregulation can lead to inflammatory skin disorders. Suppressor of cytokine signalling (SOCS) proteins are critical...
Jan 13, 2025 | Chronicles
ESDR SkinChronicles, No. 4, January 2025, by Jos P.H. Smits Paper: Steinbeck BJ, Gao XD, McElroy AN, et. al. Twin Prime Editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa. J Invest Dermatol....
Dec 10, 2024 | Chronicles
SkinChronicles, No 3, December 2024, by Marianne Bengtson Løvendorf Papers: Yi R, Poy MN, Stoffel M, Fuchs E. A skin microRNA promotes differentiation by repressing ‘stemness’. Nature. 2008 Mar 13;452(7184):225-9. PMID: 18311128. Sonkoly E, Wei T, Janson...
