Media

• 04 May Ep 39 – The skin’s barrier: a cryo-EM based overview of its architecture and stepwise formation – Lars Norlen – Link to JID overview article referred to in episode –Webcast
• 29 June Ep 41 – Building a Network Meta-Analysis – Emilie Sbidian – Webcast
  
• 21 Sept Ep 43 – In vitro and ex vivo hair research models: Key assay for clinically relevant human hair research – Janin Edelkamp – Webcast 

• 09 Feb Ep 34 – Genetic skin diseases – John McGrath and Jakub Tolar – Webcast
• 09 April Ep 38 – Skin-brain axis – Sonja Staender and Gil Yosipovitch – Webcast
• 15 June Ep 40 – Biomarkers in inflammatory skin diseases – Catherine Smith and Kilian Eyerich – Webcast

• 09 March Ep 36 – A clinician scientist journey in rare skin disorders – Edel O’Toole  – Webcast
• 19 Oct Ep 44 – The epidermis – a battleground for inflammatory skin diseases – Erwin Tschachler – Webcast
• 02 Nov Ep 45 – Progress in the understanding and treatment of Netherton syndrome  – Alain Hovnanian
  
• 14 Dec Ep 46  – Chasing triggers of skin inflammation – Michel Gilliet – Webcast

12 Jan – Ep 33 –  Webcast
Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization  (Nature Nov 2021) – Johannes U. Mayer
Transgenic Epidermal Cultures for Junctional Epidermolysis Bullosa — 5-Year Outcomes (NEJM Dec 2021) – Maximilian Kueckelhaus

 23  March– Ep 37 –   webcast
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing (Cell Metab 2021 Dec) Sebastian Willenborg
The cGAS-STING pathway drives type I IFN immunopathology in COVID-19 (Nature 2022 Jan) Jeremy Di Domizio

24 August – Ep 42 –  Webcast
Interleukin-17 governs hypoxic adaptation of injured epithelium (Science June 2022) Piotr Konieczny
Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita (American Journal of Human Genetics August 2022) Hemanth Tummala

• 27 Jan – Ep 13  Epigenomic profiling for unraveling gene regulation in skin – Andrew Lin Ji –Watch now
• 24 March – Ep 17  Proteomic Skin Atlas – Beatrice Dyring-Andersen –  Watch the video – read Q&A
• 19 May – Ep 19 Biological Models to Study Melanoma – Lionel Larue – Watch now
• 14 July – Ep 23 Mouse models of Atopic Dermatitis – Saeko Nakajima –  Watch now
• 06 Oct – Ep 27 Spatially resolved transcriptomics – technology to applications in the skin – Joakim Lundeberg –  watch now
• 01 Dec  – Ep 31 3D epidermal equivalents to study skin disease pathophysiology and disease – by Ellen van den Bogaard – watch now

• 13 Jan Ep 12 Atopic Dermatitis & Cardiovascular Disease – Sinead Langan and Sara Brown – Watch now
• 10 Mar Ep 16 Can we prevent or cure androgenetic alopecia? – Ralf Paus and Andrew Messenger – Watch now
• 30 June Ep 22 Keratins: structural v regulatory proteins – Pierre Coulombe and Birgit Lane –  Watch the video
• 08 Sept Ep 26 Is psoriasis an autoimmune disease? – Jörg Prinz and Johann Gudjonsson –  Watch now
• 17 Nov Ep 30 Is sequencing skin tumours a waste of time? David Adams and Neil Rajan  – Watch now

1. 10 Feb Ep 14 Watch the video
   • Developmental cell programs are co-opted in inflammatory skin disease presented by Gary Reynolds
   • Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model presented by Sally Dabelsteen
2. 21 April Ep 18 – Watch the video
   • Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids (Science Advances 2021) Presented by Truong San Phan
   • Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis (Journal of Experimental Medicine) presented by Min Ma
3. 16 June – Ep 21 – Watch the video
   • Analysis of Matched Skin and Gut Microbiome of Patients with Vitiligo Reveals Deep Skin Dysbiosis: Link with Mitochondrial and Immune Changes (J Invest Dermatol. 2021 ) – presented by Meri Tulic
   • Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging. (Nat Aging 1, 2021) –  presented by Emma Chambers
4. 25 August Ep 25 – Watch the video
   • Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nature cell biology –  presented by  Janis Koester
   • Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis. J Exp Med –  presented by Satoshi Nakamizo
5. 03 Nov Ep 29 Watch the video
   • Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion presented by Ruth Choa
   • EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis presented by Daisuke Nanba
     

• 24 Feb Ep 15 Chasing after simple logic behind a complex disease, pemphigus – Masa Amagai – Watch the video
• 02 June Ep 20 My personal expedition searching ingredients of inflammatory skin disease – Lars French – Watch the video
• 28 July Ep 24 How to make a mosaic cake – Veronica Kinsler 
• 20 Oct Ep 28 Psoriasis – from T cell exclusion to cytokine-based therapies – Martin Rocken – Watch the webcast
• 15 Dec Ep 32 Global goodness with scrumptious single cells – Muzlifah Haniffa –  Watch the video

• Ep 1 – Mass Cytometry Analysis Tools for Decrypting the Complexity of Biological Systems – Tiago R. Matos – webcast – Q&A
• Ep 5 – Sc-RNAseq to study skin – Patrick M. Brunner – webcast  – Q&A
• Ep 9 – CRISPR Genetic Screens to unravel novel genetic elements in epidermal homeostasis and disease – Auken Otten – Webcast

• Ep 2 – Role of Sunlight in Melanoma Pathogenesis – David Whiteman and Julia Newton-Bishop – Q&A – webcast
• Ep 8 – Vitamin D and Inflammation – Richard Gallo and Scott Byrne – Q&A  – Webcast

Ep 4 – Webcast
Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa – Presented by Cindy Orvain
Sensing of endogenous nucleic acids by ZBP1 induces necroptosis and skin inflammation – Presented by Wim Declercq

Ep 7 – Webcast

Mechanisms of stretch-mediated skin expansion at single-cell resolution – Presented by  Mariaceleste Aragona
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin – Presented by  Jérémy Di Domizio

 Ep 11 – Webcast

IgE effector mechanisms, in concert with mast cells, contribute to acquired host defense against Staphylococcus aureus – Presented by  Philipp Starkl
Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases – Presented by Stefan Haskamp
Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease – Presented by Francesca Capon

• Ep 3 – Psoriasis:A Personal Peripatetic Path of Discovery – Chris Griffiths – Q&A – webcast
• Ep 6 – A personal journey through the biology and the pathology of skin pigmentation – Alain Taïeb & Muriel Cario-André – webcast
• Ep 10 –  Beyond sticking together: My quest to understand why there are so many epidermal cadherins – Kathleen Green – Q&A  – Webcast